Plasma miRNAs Display Limited Potential as Diagnostic Tools for Endometriosis

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Plasma miRNAs as Diagnostic and Prognostic Biomarkers for Ovarian Cancer

BACKGROUND Most (70%) epithelial ovarian cancers (EOCs) are diagnosed late. Non-invasive biomarkers that facilitate disease detection and predict outcome are needed. The microRNAs (miRNAs) represent a new class of biomarkers. This study was to identify and validate plasma miRNAs as biomarkers in EOC. METHODOLOGY/PRINCIPAL FINDINGS We evaluated plasma samples of 360 EOC patients and 200 health...

متن کامل

Potential application of miRNAs as diagnostic and therapeutic tools in chronic pancreatitis

Chronic pancreatitis (CP) is a progressive inflammatory disease typified by end-stage fibrosis. This disease can also increase the risk of pancreatic cancer. The associated diagnosis, pain and other complications further add to the burden of disease management. In recent years, significant progress has been achieved in identifying miRNAs and their physiological functions, including mRNA repress...

متن کامل

Diagnostic Utility of miRNAs in Cancer

Cancer is the one of most prevalent and leading causes of death in the world. Current ad­vancements in technology improve the understanding of the pathogenesis and pathology of cancers. But, due to enlarging mortality rates, poor prognosis, and lacunae in clinical early predictive biomarkers provide an important momentum to investigate novel early diagnos­tic/prognostic markers and spec...

متن کامل

[The potential of central obesity anthropometric indicators as diagnostic tools].

OBJECTIVE It has been suggested that the indicators of centralized obesity, namely by waist-to-hip circumference ratio (WHR) and waistline measure (WM), express different metabolic disorders. Thus, a study was conducted in order to verify the diagnostic potential of the relationship between these two measures and social, behavioral, and biological determinants of centralized obesity. METHODS ...

متن کامل

miRNAs Regulation and Its Role as Biomarkers in Endometriosis

MicroRNAs (miRNAs) are small non-coding RNAs (18-22 nt) that function as modulators of gene expression. Since their discovery in 1993 in C. elegans, our knowledge about their biogenesis, function, and mechanism of action has increased enormously, especially in recent years, with the development of deep-sequencing technologies. New biogenesis pathways and sources of miRNAs are changing our conce...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism

سال: 2019

ISSN: 0021-972X,1945-7197

DOI: 10.1210/jc.2018-01464